Question

Which of the following is a suitable vector for the process of cloning in Human Genome Project (HGP)?

(a) PAC (Protozoal Artificial Chromosomes)

(b) FAC (Fungal Artificial Chromosomes)

(c) VAC (Viral Artificial Chromosomes)

(d) YAC (Yeast Artificial Chromosomes)

This question was posed to me in a job interview.

The origin of the question is Molecular Basis of Inheritance topic in chapter Molecular Basis of Inheritance of Biology – Class 12

Answer 1

Right answer is (d) YAC (Yeast Artificial Chromosomes)

For explanation: Both BAC (Bacterial Artificial Chromosomes) and YAC (Yeast Artificial Chromosomes) act as a suitable vector for the process of cloning in HGP whereas bacteria and yeast act as the host for cloning in HGP.