The correct option is (b) When the temperature rises with rigour
The explanation: Malarial Parasite can be obtained in the RBCs of the patient when the temperature of the patient rises with rigour. The high temperature of the patient signifies that the RBCs have ruptured and have released Haemozoin toxin in the blood which is responsible for high temperature after every 48 hours with chills and shivering, followed by profuse sweating.