Question

What is the approximate weight of Heavy and Light chains respectively?

(a) 50,000 Da and 25,000 Da

(b) 25,000 Da and 50,000 Da

(c) 75,000 Da and 25,000 Da

(d) 75,000 Da and 50,000 Da

This question was posed to me in an interview for internship.

My question comes from Human Health and Disease in division Human Health and Disease of Biology – Class 12

Answer 1

Correct option is (a) 50,000 Da and 25,000 Da

To elaborate: Each antibody molecule has four peptide chains, two long chains called heavy or H chain each of molecular weight 50,000 Da and two short chains called light or L chains each of approximate molecular weight 25,000 Da.