Right choice is (a) True
To explain I would say: Opioids include Semisynthetic drugs and Synthetic opioids. Semisynthetic drugs are produced from morphine and thebaine and include hydromorphone, oxycodone, heroin. Synthetic opioids are methadone, pethidine, meperidine, propoxyphene, diphenoxylate, pentazocine, etc.