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The adoption of continuous culture is difficult for which type of systems?

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The adoption of continuous culture is difficult for which type of systems?

(a) Microbial

(b) Animal

(c) Plant

(d) Bacterial

I have been asked this question in class test.

Question is taken from Comparison of Batch and Continuous Culture in Industrial Processes in section Microbial Growth Kinetics of Bioprocess Engineering

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Correct answer is (b) Animal

To explain: The adoption of continuous culture for animal cell products is even more complex than for microbial systems. Furthermore, it is difficult to monitor the genetic stability of cells which are immobilized in a large scale reactor system. Thus, large scale animal cell products are still produced by batch methods.

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