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Local anesthetics act by _____________ the ion channels.

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Local anesthetics act by _____________ the ion channels.

(a) inactivating

(b) opening

(c) closing

(d) mutating

The question was posed to me in class test.

My question is from Cellular Membranes in portion Cellular Membranes of Cell Biology

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Right answer is (c) closing

Easiest explanation: Local anesthetics act by closing the ions channels present in the membranes of sensory cells and neurons. As a result no action potential is generated and information can not be sent to the brain about events occurring at the skin or teeth.

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