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In addition to amyloid-β peptide, which other protein is misfolded in the brains of Alzheimer’s disease patients?

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In addition to amyloid-β peptide, which other protein is misfolded in the brains of Alzheimer’s disease patients?

(a) Alpha

(b) Zau

(c) Theta

(d) Tau

I have been asked this question by my school principal while I was bunking the class.

My doubt stems from Chemical Basis of Life in portion Chemical Basis of Life of Cell Biology

1 Answer

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Best answer
The correct choice is (d) Tau

To explain I would say: The tau-protein functions as a part of nerve cell’s cytoskeleton. In patients with Alzheimer’s this protein develops into bundles of tangle cellular filaments called neurofibrillary tangles (or NFTs) as a result of misfolding.

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