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Which residues are present in histone proteins?

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Which residues are present in histone proteins?

(a) Lysine & proline

(b) Glutamic acid & aspartic acid

(c) Arginine & Histidine

(d) Serine & Cysteine

The question was asked during a job interview.

The above asked question is from Chemical Basis of Life topic in chapter Chemical Basis of Life of Cell Biology

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Right answer is (c) Arginine & Histidine

The explanation is: DNA is a negatively charged molecule that wounds around histone proteins. They are rich in both arginine and histidine residues (both are positively charged Amino acids) which helps the negatively charged DNA bind to it. This forms a strong ionic bond formation allowing the DNA to be tightly packed into chromosomes.

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