Question

Which of the following is untrue?

(a) Protein folding occurs in Golgi bodies

(b) Protein folding is assisted by a protein molecule called Chaperone

(c) Transmembrane or organelle proteins contain a signal peptide

(d) Proteins are present in cytoplasm and cell organelles of all cells

I had been asked this question during an interview.

This question is from Types of Biological Molecules topic in chapter Structures and Functions of Biological Molecules of Cell Biology

Answer 1

Right option is (a) Protein folding occurs in Golgi bodies

The explanation: The folding of proteins occurs in the lumen of the Endoplasmic Reticulum (ER). A newly synthesized protein undergoes a series of modifications in the ER with the help of a number of molecular chaperones and folding enzymes that all together assist its proper folding and subsequent release from ER. The majority of ER proteins are dedicated to the folding of proteins. Golgi bodies help in the proper packaging and transport of proteins.