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The DNA binding proteins bind at the _______________

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The DNA binding proteins bind at the _______________

(a) Minor groove

(b) Major groove

(c) Phosphate molecules

(d) Pentose sugars

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The above asked question is from Genes, Chromosomes and Genomes in division Bioenergetics, Enzymes, Metabolism, Genes, Chromosomes and Genomes of Cell Biology

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Right answer is (b) Major groove

For explanation: The DNA double strands are present as a double-helix as they wound around each another. Due to base stacking, alternative minor and major grooves are formed in the helix. Major groove provide the site for DNA protein binding.

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