Question

Which of the following enzyme present in the rough endoplasmic reticulum removes the signal sequence from nascent polypeptides?

(a) signal oxidase

(b) signal peptidase

(c) olisaccharyltransferase

(d) luciferase

The question was asked in my homework.

I want to ask this question from Cytoplasmic Membrane Systems in section Cytoplasmic Membrane Systems of Cell Biology

Answer 1

Right choice is (b) signal peptidase

For explanation: After the nascent polypeptide reaches the cisterna of endoplasmic reticulum, it is acted upon by a variety of enzymes. One such enzyme is signal peptidase which removes the hydrophobic signal sequence from the peptide.