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Subcellular fragmentation is a technique to study the endomembrane system, based on _____________ of the cells.

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Subcellular fragmentation is a technique to study the endomembrane system, based on _____________ of the cells.

(a) homogenization

(b) degradation

(c) labeling

(d) freezing

This question was posed to me in an online interview.

My question comes from Cytoplasmic Membrane Systems in division Cytoplasmic Membrane Systems of Cell Biology

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Best answer
The correct choice is (a) homogenization

Best explanation: Subcellular fragmentation is a technique that elucidates the molecular composition of an organelle. The cells are first ruptured by homogenization and as a result their membranes and internal structures get fragmented and form vesicles. Since the vesicles derived from different organelles (like ribosome, endoplasmic reticulum etc.) have different properties, they get separated from one another.

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