Question

Which of the following about spontaneous folding is false?

(a) It involves the initial formation of highly compact structure

(b) It involves initial formation of a local secondary structure

(c) It is essentially a random process

(d) It may be defective in some human diseases

I had been asked this question in an online interview.

My question comes from Protein Denaturation and Folding in section Three Dimensional Structure Of Proteins and Protein Function of Biochemistry

Answer 1

The correct choice is (c) It is essentially a random process

The explanation: Protein folding is a spontaneous process aided by the hydrophobic interactions which is not random.