Question

When one molecule of glucose is oxidized to two molecules of lactate during anaerobic glycolysis, which of the following statements is false?

(a) Glyceraldehyde 3-P dehydrogenase reaction produces 2 ATP molecules

(b) Lactate dehydrogenase reaction produces no ATP

(c) Pyruvate kinase reaction produces 2 ATP molecules

(d) Phosphofructokinase-1 reaction uses 1 ATP molecule

I got this question in an interview for internship.

My question is based upon Fates of Pyruvate under Anaerobic Conditions: Fermentation topic in section Principles of Bioenergetics and Glycolysis of Biochemistry

Answer 1

Correct choice is (a) Glyceraldehyde 3-P dehydrogenase reaction produces 2 ATP molecules

To explain: When one molecule of glucose is oxidized to two molecules of lactate during anaerobic glycolysis, Glyceraldehyde 3-P dehydrogenase reaction does not produce 2 ATP molecules.