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Which is the major factor(s) determining whether glucose is oxidized by aerobic or anaerobic glycolysis?

(a) Ca^+2

(b) FADH2

(c) NADH and the ATP/ADP ratio

(d) Presence of high AMP

This question was posed to me in exam.

My question is taken from Fates of Pyruvate under Anaerobic Conditions: Fermentation in section Principles of Bioenergetics and Glycolysis of Biochemistry

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Right choice is (c) NADH and the ATP/ADP ratio

The best I can explain: NADH and the ATP/ADP ratio are the major factors determining whether glucose is oxidized by aerobic or by anaerobic glycolysis.

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