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Aggregation of neurofilaments leads to ____________

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Aggregation of neurofilaments leads to ____________

(a) vision disorders

(b) skin disorders

(c) lung disorders

(d) neurodegenerative disorders

The question was posed to me in a national level competition.

My doubt is from Cytoskeleton in chapter Cytoskeleton and Cell Motility of Cell Biology

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Correct choice is (d) neurodegenerative disorders

Easiest explanation: Neurofilaments are the intermediate filaments that constitute mature neuronal cells. Aggregation of these neurofilaments blocks axonal transport, associated with neurodegenerative disorders like Alzheimer’s and Parkinson’s disease.

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