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The first step in FASTA alignment id to arrange the sequences in matrices’ rows and columns in order to be analyzed.

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The first step in FASTA alignment id to arrange the sequences in matrices’ rows and columns in order to be analyzed.

(a) True

(b) False

The question was asked in an interview for internship.

The query is from FASTA in section Database Similarity Searching of Bioinformatics

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Correct choice is (b) False

The explanation: The first step in FASTA alignment is to identify ktups between two sequences by using the hashing strategy. This strategy works by constructing a look up table that shows the position of each ktup for the two sequences under consideration. The mentioned method is similar to that of BLAST.

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