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Lysosomal storage disorders are caused due to ______________

(a) absence of lysosomes

(b) absence of a single lysosome

(c) absence of integral membrane proteins

(d) accumulation of lipofuschin granules

This question was posed to me by my college director while I was bunking the class.

This question is from Cytoplasmic Membrane Systems in division Cytoplasmic Membrane Systems of Cell Biology

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The correct answer is (b) absence of a single lysosome

The explanation is: Lysosomal storage disorders are caused due to the absence of a single lysosomal enzyme. For example, the ‘Pompe disease’ is caused by the absence of alpha-glucosidase.

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