Question

Which property of p53 enables it to prevent the development of cancer?

(a) It is a transcription factor that causes protein production which stimulates the cell cycle

(b) It prevents replication of cells with damaged DNA

(c) It prevents cells from triggering apoptosis

(d) It stimulates synthesis of DNA repair enzymes that replace telomere sequence lost during cell division

I had been asked this question during an internship interview.

I'm obligated to ask this question of Oncogenes, Tumor Suppressor Genes and Programmed Cell Death topic in chapter Biosignalling of Biochemistry

Answer 1

Right answer is (b) It prevents replication of cells with damaged DNA

To explain I would say: p53 prevents replication of cells with damaged DNA.