Question

RNA structures can be experimentally determined using _____

(a) X-ray crystallography techniques only

(b) NMR techniques only

(c) X-ray crystallography or NMR techniques

(d) Gel electrophoresis

I have been asked this question during an interview.

This question is from Types of RNA Structures in portion RNA Structure Prediction of Bioinformatics

Answer 1

The correct answer is (c) X-ray crystallography or NMR techniques

Explanation: However, the two approaches are extremely time consuming and expensive. As a result, computational prediction has become an attractive alternative. Option Gel electrophoresis, here, becomes irrelevant as it comes to the structure of RNA.