Question

There are two types matrices involved in the study- score matrices and trace matrices.

(a) True

(b) False

This question was addressed to me in final exam.

My query is from Needleman topic in portion Multiple Sequence Alignment of Bioinformatics

Answer 1

Correct option is (a) True

To explain: The Needleman-Wunsch algorithm consists of three steps where these matrices play their role as follows:

i. Initialization of the score matrix

ii. Calculation of scores and filling the traceback matrix

iii. Deducing the alignment from the traceback matrix