Question

In ab initio methods, a quantitative approach such as dynamic programming can be used to assemble a final structure with optimal base-paired regions.

(a) True

(b) False

I have been asked this question in exam.

The query is from Ab Initio Approach topic in chapter RNA Structure Prediction of Bioinformatics

Answer 1

Right option is (a) True

To explain: In this approach, an RNA sequence is compared with itself. A scoring scheme is applied to fill the matrix with match scores based on Watson–Crick base complementarity.