Question

___________ of covariation can be ___________ to the RNA structure and functions.

(a) Any lack, deleterious

(b) Any lack, benign

(c) Any abundance, deleterious

(d) Any inadequacy, advantageous

I got this question in a job interview.

Question is taken from Comparative Approach in portion RNA Structure Prediction of Bioinformatics

Answer 1

Correct answer is (a) Any lack, deleterious

For explanation I would say: Based on this rule, algorithms can be written to search for the covariation patterns after a set of homologous RNA sequences are properly aligned. The detected correlated substitutions help to determine conserved base pairing in a secondary structure.