Question

The type of algorithm that _____ predefined alignment is ______ for reasonably conserved sequences.

(a) doesn’t require, more successful

(b) requires, less successful

(c) doesn’t require, relatively successful

(d) requires, relatively successful

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Answer 1

The correct option is (d) requires, relatively successful

Best explanation: The requirement for using this type of program is an appropriate set of homologous sequences that have to be similar enough to allow accurate alignment, but divergent enough to allow covariations to be detected. If this condition is not met, correct structures cannot be inferred.