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Unfolding of regular secondary protein structure causes ____________

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in Biochemistry by (89.2k points)
Unfolding of regular secondary protein structure causes ____________

(a) Large decrease in the entropy of the protein

(b) Little increase in the entropy of protein

(c) No change in the entropy of the protein

(d) Large increase in the entropy of the protein

The question was asked during an online exam.

My doubt is from Bioenergetics and Thermodynamics topic in portion Principles of Bioenergetics and Glycolysis of Biochemistry

1 Answer

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by (65.4k points)

Unfolding of regular secondary protein structure causes:

(d) Large increase in the entropy of the protein

When a protein unfolds, the ordered structure of the secondary protein conformation (such as alpha-helices and beta-sheets) becomes disordered. This increase in disorder results in a large increase in the entropy of the protein.

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