Question

A point mutation that replaces a purine with another purine, or a pyrimidine with another pyramidine ____________

(a) Nonsense mutation

(b) Silent mutation

(c) Transition mutation

(d) Transversion

I got this question during an interview for a job.

My enquiry is from DNA Repair topic in section DNA, RNA and Protein Metabolism of Biochemistry

Answer 1

Correct answer is (c) Transition mutation

The best I can explain: Nonsense mutation (point mutation) results in a premature stop codon.

Transversion refers to substitution of a purine for a pyrimidine or vice-versa.

If the mutation has a negligible effect on the function of a gene, it is known as a silent mutation.