Question

Glutamate is metabolically converted to α-ketoglutarate and NH4^+ by a process ___________

(a) Oxidative deamination

(b) Transamination

(c) Reductive deamination

(d) Deamination

This question was posed to me during a job interview.

I'd like to ask this question from Metabolic Fates of Amino Groups topic in portion Amino Acid Oxidation and the Production of Urea of Biochemistry

Answer 1

Correct option is (a) Oxidative deamination

To explain I would say: Glutamate is metabolically converted to α-ketoglutarate and NH4^+ by a process oxidative deamination catalyzed by L-glutamate dehydrogenase.