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The Genetic Algorithm method has been recently adapted for MSA(Multiple Sequence Alignment) by Corpet (1998).

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The Genetic Algorithm method has been recently adapted for MSA(Multiple Sequence Alignment) by Corpet (1998).

(a) True

(b) False

The question was asked during an online interview.

This intriguing question comes from Iterative Methods of Multiple Sequence Alignment topic in section Multiple Sequence Alignment of Bioinformatics

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Correct choice is (b) False

Easy explanation: The genetic algorithm is a general type of machine-learning algorithm that has no direct relationship to biology and that was invented by computer scientists. The method has been recently adapted for MSA (Multiple Sequence Alignment) by Notredame and Higgins (1996) in a computer program package called SAGA (Sequence Alignment by Genetic Algorithm).

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