Question

Which of the following is wrong about GenBank DNA Sequence Entry?

(a) The information is organized into fields, each with an identifier, shown as the first text on each line

(b) In some entries, these identifiers may be abbreviated to two letters, e.g., RF for reference

(c) Some identifiers may have additional subfields

(d) The CDS subfield in the field FEATURES does not offer the amino acid sequence

I got this question in a job interview.

I'd like to ask this question from Sequence Formats & Computer Storage of Sequences in chapter Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer 1

The correct choice is (d) The CDS subfield in the field FEATURES does not offer the amino acid sequence

Best explanation: The CDS subfield in the field FEATURES gives the amino acid sequence obtained by translation of known and potential open reading frames. The format of a database entry in GenBank, the NCBI nucleic acid and protein sequence database, is as follows: Information describing each sequence entry is given, including literature references, information about the function of the sequence, locations of mRNAs and coding regions, and positions of important mutations.