Question

The burial of surface area (or the maximization of surface contact) is an approximation of the effect of shape complementarity.

(a) True

(b) False

I have been asked this question in an international level competition.

My doubt is from Molecular Complementarity topic in chapter Predicting the Structure of Protein – Biomolecular Interactions of Bioinformatics

Answer 1

Right option is (a) True

To elaborate: However, since no distinction is generally made between polar and non-polar surface area this is an approximation. As burial of the former is unfavorable or neutral the sentence is held true.