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An approach to classification of genes that encode enzymes is to examine relationships among multiple enzymes that perform the same biochemical function in the same organism.

(a) True

(b) False

I got this question by my college professor while I was bunking the class.

This interesting question is from Functional Classification of Genes topic in division Genome Analysis of Bioinformatics

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Right answer is (a) True

For explanation: Although catalyzing the same reaction, these enzymes showed variations in metabolic regulation of their activity. More than one-half of multiple enzymes in E. coli share significant sequence similarity; i.e., they are paralogs. However, the remainder do not share any sequence similarity.

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