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The rate limiting step of Michaelis Menten kinetics is _________

(a) Complex formation step

(b) Non-complex formation step

(c) Complex dissociation step

(d) Non- complex dissociation step

This question was posed to me in my homework.

My question comes from General Reaction Kinetics for Biological Systems in chapter Homogenous Reactions of Bioprocess Engineering

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Correct choice is (c) Complex dissociation step

To explain: The rate limiting step in the enzyme catalyzed transformation of substrate S into product P is the breakdown of the ES complex. The rate-limiting step is usually the product formation step.

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