Question

What do you mean by glycosylation?

(a) Addition of sugar

(b) Non-addition of sugar

(c) Lysis of sugar moieties

(d) Blockage of sugar molecules

The question was posed to me in an online interview.

This intriguing question originated from Guidelines for Choosing Host-Vector Systems in division Utilizing Genetically Engineered Organisms & Medical Applications of Bioprocess Engineering of Bioprocess Engineering

Answer 1

The correct answer is (a) Addition of sugar

Easy explanation: Glycosylation is a critical function of the biosynthetic-secretory pathway in the endoplasmic reticulum (ER) and Golgi apparatus. Approximately half of all proteins typically expressed in a cell undergo this modification, which entails the covalent addition of sugar moieties to specific amino acids.