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Chromosome compaction at prophase requires ______________________

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Chromosome compaction at prophase requires ______________________

(a) DNA helicase

(b) DNA polymerase

(c) RNA polymerase

(d) Topoisomerase II

The question was asked in my homework.

This is a very interesting question from Cellular Reproduction in portion DNA Replication and Repair, Cellular Reproduction of Cell Biology

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Correct choice is (d) Topoisomerase II

The best I can explain: Chromosome compaction at prophase requires topoisomerase II which is present as a part of mitotic chromosome scaffold along with the multiprotein complex condensing.

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