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Presence of an extra copy of which chromosome leads to the Doen syndrome?

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Presence of an extra copy of which chromosome leads to the Doen syndrome?

(a) chromosome 9

(b) chromosome 11

(c) chromosome 17

(d) chromosome 21

The question was posed to me by my school principal while I was bunking the class.

My question is based upon Cellular Reproduction topic in chapter DNA Replication and Repair, Cellular Reproduction of Cell Biology

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Correct option is (d) chromosome 21

The best explanation: Chromosome 21, consisting of fewer than 400 genes is the smallest human chromosome, the presence of an extra copy of this gene (trisomy 21) leads to the Down syndrome characterized by various mental impairments.

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