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First artificially synthesized gene sequence was _________________

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First artificially synthesized gene sequence was _________________

(a) poly(U)

(b) poly(A)

(c) poly(G)

(d) poly(C)

The question was asked during an online interview.

Enquiry is from Gene Expression in chapter Gene Expression of Cell Biology

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Right answer is (a) poly(U)

Easy explanation: First artificial genetic message was synthesized by Marshall Nirenberg and Heinrich Matthaei, composed of uridine residues called poly(U). They were able to synthesize bacterial proteins using the poly(U), ribosomes, amino acids and soluble factors.

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