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Circular DNAs are negatively supercoiled.

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in Cell Biology by (121k points)
Circular DNAs are negatively supercoiled.

(a) True

(b) False

The question was posed to me in an interview.

My enquiry is from Genome Structure topic in portion Nature of Genome of Cell Biology

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The correct choice is (a) True

The best I can explain: Circular DNAs extant in nature include mitochondrial, bacterial and viral DNA. These are invariably negatively supercoiled i.e. underwound. An underwound DNA has greater number of basepairs per turn of the helix.

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