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Endostatin is a ___________________

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Endostatin is a ___________________

(a) angiogenesis inhibitor

(b) angiogenesis promoter

(c) transcription factor

(d) cell surface receptor

I have been asked this question in class test.

My enquiry is from Combating Cancer in division Cancer of Cell Biology

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Best answer
Correct answer is (a) angiogenesis inhibitor

The best explanation: Endostatin is a naturally occurring inhibitor of angiogenesis – the process of formation of new blood vessels. It is a 20 kilo Dalton fragment of C-terminal of Collagen XVIII, which specifically inhibits the proliferation of endothelial cells.

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