When sigma subunit dissociates from the RNA polymerase what happens to the DNA binding clamp of the core?

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When sigma subunit dissociates from the RNA polymerase what happens to the DNA binding clamp of the core?

1 Answer

Frank · Answer 1 · 2021-10-05T23:07:37+0000

Right option is (d) It is phophorylated and ubiquitination occurs

Easiest explanation: In the absence of the sigma subunit initially the RNA Pol clamp is closed. Sigma makes a window of open clamp conformation when RNA pol loads on the DNA. When sigma dissociates the clamp closes again around the DNA preventing the pol to fall off.

When sigma subunit dissociates from the RNA polymerase what happens to the DNA binding clamp of the core?

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