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If a bacteria is facing lack of carbon sources in the media, which sigma factor concentration is expected to increase?

(a) Sigma E

(b) Sigma S

(c) Sigma 70

(d) Sigma 32

The question was asked during an interview.

My question is based upon Transcription in Prokaryotes : Sigma Factor in division Gene Expression : Transcription Prokaryotes of Cytogenetics

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Correct choice is (b) Sigma S

Explanation: Sigma S is synthesized when the cell is under stressed conditions as in stationary phase. It transcribes rpo S gene which helps to overcome carbon starvation in stationary phase. Sigma E works in extreme conditions of shock, while sigma 70 and 43 work in normal conditions.

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