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If there is a non-disjunction in the X chromosome, the progeny being XXY, what will be the constitution of the chromosome(s) in the gamete?

(a) X and Y

(b) X and XY

(c) XX and Y

(d) XXY with no separation

I had been asked this question in semester exam.

Question is from Chromosomal Theory of Inheritance topic in division Chromosomal Basis of Inheritance of Cytogenetics

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Right choice is (b) X and XY

Best explanation: The non-disjunction results in the production of XXY. Then these alleles separate as X and XY respectively. The male progeny in this case will be XYY and the females XXY but the XXX dies due to no gene compensation.

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