Question

If co-incorporation probabilities are given as p,o 0.1; o,r 0.02 ; p,r 0.15. What is the gene order

(a) o r p

(b) o p r

(c) r o p

(d) Can’t be determined due to insufficient data

The question was posed to me in examination.

The above asked question is from Gene Mapping in Bacteria by Transformation topic in section Genomics : The Mapping and Sequencing of Genomes of Cytogenetics

Answer 1

Right option is (b) o p r

Easy explanation: This is because o and p have an appreciable degree of co-incorporation, as does r and p but o and r have much lower degree of co-incorporation. This shows that p must be at the middle of o and r.