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Which initiation factor prevents association of ribosome when not bound to mRNA?

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Which initiation factor prevents association of ribosome when not bound to mRNA?

(a) IF1

(b) IF2

(c) IF3

(d) IF4

I have been asked this question in an online interview.

The question is from Initiation in portion Gene Expression : Translation of Cytogenetics

1 Answer

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Best answer
Correct choice is (c) IF3

The best explanation: The IF3 binds to the 30S subunit and prevents association of 30S and 50S subunit when the ribosome is not bound to mRNA. It also helps in binding t the mRNA.

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