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Holliday intermediate could be mistaken for ___________ under microscope.

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Holliday intermediate could be mistaken for ___________ under microscope.

(a) Hetero chromatin

(b) Circular plasmid

(c) Linear extracellular chromosome

(d) Broken chromosome

I got this question in an internship interview.

My query is from Homologous DNA Recombination topic in portion Genetic Recombination of Cytogenetics

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Correct option is (b) Circular plasmid

Easy explanation: Circular chromosomes can appear as Holliday intermediate as when they are twisted the twist points may appear as crossing over sites.

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