Question

What is the function of a granulating agent in drug formulation?

(a) Promote cohesive compacts

(b) Added if the required dosage is inadequate so that necessary bulk can be produced

(c) Tablets can disintegrate easily

(d) Used as solubilizer

This question was addressed to me by my college director while I was bunking the class.

My question comes from Dosage Form Factors Affecting Drug Absorption in section Absorption of Drugs of Drug Biotechnology

Answer 1

Right choice is (a) Promote cohesive compacts

Easy explanation: Binders and granulating agents are used to hold powders together to form compact tablets. They help in the formation of granules and promote cohesive compacts for compressible materials. It ensures that the tablet remains intact after compression.