Question

Which of these is not a characteristic of tablet formulation by Agglomerative phase of the communication process?

(a) Tablets are stronger

(b) Usage of more binding agent

(c) Rapid dissolution

(d) Increase in internal surface area of the granules

I got this question at a job interview.

This interesting question is from Dosage Form Factors Affecting Drug Absorption in division Absorption of Drugs of Drug Biotechnology

Answer 1

The correct answer is (b) Usage of more binding agent

To elaborate: Agglomerative phase of communication is a recent process which involves grinding the drug in a ball mill for a long time to affect spontaneous agglomeration. The tablets so produced were stronger and showed rapid dissolution in comparison to tablets made by another method. It gave an increased internal surface area of the granules prepared by APOC method.