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A large amount of binders tends to increase the hardness of tablets.

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A large amount of binders tends to increase the hardness of tablets.

(a) True

(b) False

I had been asked this question during an internship interview.

This interesting question is from Dosage Form Factors Affecting Drug Absorption topic in division Absorption of Drugs of Drug Biotechnology

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Right answer is (a) True

The explanation is: The proportion of binders in any tablet formulation is very critical. Increase in the amount of binders tends to increase the hardness and decrease the disintegration and dissolution rates of the tablet.

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