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The lethal mutation that is seen in the yellow mice is due to _______________ mutation

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The lethal mutation that is seen in the yellow mice is due to _______________ mutation

(a) Insertion

(b) Deletion

(c) Non-sense

(d) Frame shift

This question was addressed to me during an internship interview.

Question is from Lethal Alleles in chapter Extension and Deviation from Mendelian Genetic Principles of Cytogenetics

1 Answer

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Best answer
Right answer is (b) Deletion

The best explanation: The mutation seen in this case is deletion mutation. The raly gene and the agouti genes lie side by side. Deletion of the gene sequence of Rally and the promoter of Agouti gives this colour.

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