Question

Compounds excreted in bile is classified into 3 categories. Which one of the following does not come under the categories?

(a) Drugs with bile/plasma concentration ratio approximately 1

(b) Drugs with bile/plasma concentration ratio between 10-1000

(c) Drugs with bile/plasma concentration ratio of less than 1

(d) Drugs with bile/plasma concentration ratio above 1000

This question was addressed to me in an international level competition.

My question is from Drugs Excretion topic in portion Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

The correct option is (d) Drugs with bile/plasma concentration ratio above 1000

The explanation: The categories are divided into Group A, Group B, Group C. Group A has drugs with bile/plasma concentration ratio approximately 1 e.g. sodium. Group B has drugs with bile/plasma concentration ratio between 10 -1000 e.g. creatinine. Group C has drugs with bile/plasma concentration ratio less than 1 e.g. sucrose.