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Which of the following compounds are used as agents to determine Glomerular Filtration Rate?

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Which of the following compounds are used as agents to determine Glomerular Filtration Rate?

(a) Calcium ion

(b) Albumin

(c) Creatinine

(d) Calcium carbonate

This question was posed to me by my school principal while I was bunking the class.

My doubt stems from Drugs Excretion topic in portion Prodrugs & Excretion of Drugs of Drug Biotechnology

1 Answer

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Best answer
Right choice is (c) Creatinine

To elaborate: GFR is determined by agent which is excreted exclusively by glomerular filtration and is neither secreted nor reabsorbed in the tubules. The excretion rate of such compounds is 120-130 ml/min. The compounds used are creatinine, insulin, mannitol, sodium thiosulfate.

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